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Sexual & Hormonal Health

Peptides studied in relation to libido, sexual function, and hormonal signaling. A few compounds here have meaningful human research, while others are far more preliminary, so we are careful to separate the two and to keep the tone educational, not promotional.

Peptides in this category

7 profiles
Moderate evidence Sexual & Hormonal Health

Enclomiphene

Enclomiphene

Enclomiphene is one of the two isomers that make up the fertility drug clomiphene. It has been studied in men to raise testosterone while preserving sperm production. It reached late-stage human trials but is not currently approved by the FDA as a standalone product.

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Moderate evidence Sexual & Hormonal Health

Gonadorelin

Gonadorelin

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), the natural signal that tells the pituitary to release reproductive hormones. It is an approved drug historically used in fertility evaluation and treatment, given under medical supervision.

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Limited evidence Sexual & Hormonal Health

Kisspeptin-10

Kisspeptin-10

Kisspeptin-10 is a short fragment of kisspeptin, a natural hormone that helps trigger reproductive hormone release. It is an active area of academic research into fertility and sexual response, but it is not an approved medicine and remains mostly in the research setting.

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Limited evidence Sexual & Hormonal Health

Melanotan II

Melanotan II

Melanotan II is a synthetic melanocortin peptide that both darkens skin and can increase sexual arousal. It is widely sold online as an unregulated injectable for tanning, but it is not an approved medicine and has been flagged by regulators over safety concerns.

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Moderate evidence Sexual & Hormonal Health

Oxytocin

Oxytocin

Oxytocin is a natural hormone and an approved medicine, used in obstetrics to induce labor and control bleeding after birth. It is also widely studied for social and behavioral effects, but evidence for those popular uses, especially intranasal sprays, is far less established.

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Moderate evidence Sexual & Hormonal Health

PT-141

Bremelanotide

PT-141, known by the drug name bremelanotide, is an approved medicine (Vyleesi) for a specific type of low sexual desire in premenopausal women. It works through brain melanocortin receptors rather than the blood-flow pathway used by drugs like sildenafil.

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Moderate evidence Sexual & Hormonal Health

Triptorelin

Triptorelin

Triptorelin is an approved medicine (a GnRH agonist) used to lower sex-hormone levels in conditions such as advanced prostate cancer, endometriosis, and central precocious puberty. It is a well-established prescription drug given by injection under medical supervision.

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